Maternal High-Fat Diet Modulates Hepatic Glucose, Lipid Homeostasis and Gene Expression in the PPAR Pathway in the Early Life of Offspring

Maternal High-Fat Diet Modulates Hepatic Glucose, Lipid Homeostasis and Gene Expression in the PPAR Pathway in the Early Life of Offspring

Maternal dietary modifications determine the susceptibility to metabolic diseases in adult life. However, whether maternal high-fat feeding can modulate glucose and lipid metabolism in the early life of offspring is less understood. Furthermore, we explored the underlying mechanisms that influence t...

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Bibliographic Details
Main Authors: Jia Zheng, Xinhua Xiao, Qian Zhang, Miao Yu, Jianping Xu, Zhixin Wang
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:International Journal of Molecular Sciences
Subjects:
maternal high-fat diet
peroxisome proliferator-activated receptor
glucose and lipid homeostasis
weaning
offspring
Online Access:http://www.mdpi.com/1422-0067/15/9/14967

Internet

http://www.mdpi.com/1422-0067/15/9/14967

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