The PKD inhibitor CID755673 enhances cardiac function in diabetic db/db mice.

The development of diabetic cardiomyopathy is a key contributor to heart failure and mortality in obesity and type 2 diabetes (T2D). Current therapeutic interventions for T2D have limited impact on the development of diabetic cardiomyopathy. Clearly, new therapies are urgently needed. A potential th...

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Bibliographic Details
Main Authors: Kylie Venardos, Kirstie A De Jong, Mansour Elkamie, Timothy Connor, Sean L McGee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370864?pdf=render