TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model

TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model

<p>Abstract</p> <p>Background</p> <p>The T-box transcription factor TBX3 is necessary for early embryonic development and for the normal development of the mammary gland. Homozygous mutations, in mice, are embryonic lethal while heterozygous mutations result in perturbe...

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Bibliographic Details
Main Authors: Gulsen Gultekin, Shang Xiying, Esmailpour Taraneh, Liu Jing, Liu Andy, Huang Taosheng
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/11/65

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