TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model
<p>Abstract</p> <p>Background</p> <p>The T-box transcription factor TBX3 is necessary for early embryonic development and for the normal development of the mammary gland. Homozygous mutations, in mice, are embryonic lethal while heterozygous mutations result in perturbe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-10-01
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Series: | BMC Developmental Biology |
Online Access: | http://www.biomedcentral.com/1471-213X/11/65 |