Acetylcholine Promotes ROS Detoxification Against Hypoxia/reoxygenation-Induced Oxidative Stress Through FoxO3a/PGC-1α Dependent Superoxide Dismutase

Acetylcholine Promotes ROS Detoxification Against Hypoxia/reoxygenation-Induced Oxidative Stress Through FoxO3a/PGC-1α Dependent Superoxide Dismutase

Background/Aims: Acetylcholine (ACh) is known to modulate the cardiac redox environment and thereby suppress reactive oxygen species (ROS) generation during oxidative stress. However, there is little information about its regulation on ROS clearance. Here we investigate the beneficial effects of ACh...

Full description

Bibliographic Details
Main Authors: Lei Sun, Wei-Jin Zang, Hao Wang, Mei Zhao, Xiao-Jiang Yu, Xi He, Yi Miao, Jun Zhou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
PGC-1α
FoxO3a
Hypoxia/reoxygenation
Oxidative stress
Superoxide dismutase
Acetylcholine
Online Access:http://www.karger.com/Article/FullText/366364

Internet

http://www.karger.com/Article/FullText/366364

Similar Items