Rice Bran and Vitamin B6 Suppress Pathological Neovascularization in a Murine Model of Age-Related Macular Degeneration as Novel HIF Inhibitors

Rice Bran and Vitamin B6 Suppress Pathological Neovascularization in a Murine Model of Age-Related Macular Degeneration as Novel HIF Inhibitors

Pathological neovascularization in the eye is a leading cause of blindness in all age groups from retinopathy of prematurity (ROP) in children to age-related macular degeneration (AMD) in the elderly. Inhibiting neovascularization via antivascular endothelial growth factor (VEGF) drugs has been used...

Full description

Bibliographic Details
Main Authors: Mari Ibuki, Deokho Lee, Ari Shinojima, Yukihiro Miwa, Kazuo Tsubota, Toshihide Kurihara
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxia-inducible factor
age-related macular degeneration
vascular endothelial growth factor
food ingredients
rice bran
vitamin B6
Online Access:https://www.mdpi.com/1422-0067/21/23/8940

Internet

https://www.mdpi.com/1422-0067/21/23/8940

Similar Items