A Chitosan-Based Micellar System as Nanocarrier For the Delivery of Paclitaxel

In this study, a redox-sensitive chitosan derivative with modifications by cholesterol, sulfhydryl, and mPEG (mPEG-CS(SH)-CHO) was successfully synthesized and characterized. Due to its amphiphilicity, the conjugate could spontaneously form micelles in an aqueous environment. The optimized paclitaxe...

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Bibliographic Details
Main Authors: Yang Han, Na Liang, Pengfei Yan, Yoshiaki Kawashima, Fude Cui, Shaoping Sun
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/2/380