Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity
Abstract Cellular heterogeneity in cancer represents a significant challenge. In order to develop effective and lasting therapies, it is essential to understand the source of this heterogeneity, and its role in tumor progression and therapy resistance. Here, we consider not only genetic and epigenet...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-04-01
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| Series: | npj Breast Cancer |
| Online Access: | https://doi.org/10.1038/s41523-017-0012-z |