Non-structural Proteins of Severe Fever With Thrombocytopenia Syndrome Virus Suppress RNA Synthesis in a Transcriptionally Active cDNA-Derived Viral RNA Synthesis System

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by the tick-borne SFTS bunyavirus (SFTSV) resulting in a high fatality rate up to 30%. SFTSV is a negative-strand RNA virus containing three single-stranded RNA genome segments designated as L, M, and S, whic...

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Bibliographic Details
Main Authors: Fuli Ren, Shu Shen, Yun-Jia Ning, Qiongya Wang, Shiyu Dai, Junming Shi, Min Zhou, Hualin Wang, Chaolin Huang, Ding-Yu Zhang, Fei Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
NSs
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.709517/full