Triplex Forming Oligonucleotides – Tool for Gene Targeting
This review deals with the antigene strategy whereby an oligonucleotide binds to the major or minor groove of double helical DNA where it forms a local triple helix. Preoccupation of this article is triplex-forming oligonucleotides (TFO). These are short, synthetic single-stranded DNAs that recogniz...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karolinum Press
2004-01-01
|
| Series: | Acta Medica |
| Subjects: | |
| Online Access: | https://actamedica.lfhk.cuni.cz/47/3/0151/ |