A novel strategy to improve protein secretion via overexpression of the SppA signal peptide peptidase in Bacillus licheniformis

A novel strategy to improve protein secretion via overexpression of the SppA signal peptide peptidase in Bacillus licheniformis

Abstract Background Signal peptide peptidases play an important role in the removal of remnant signal peptides in the cell membrane, a critical step for extracellular protein production. Although these proteins are likely a central component for extracellular protein production, there has been a lac...

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Bibliographic Details
Main Authors: Dongbo Cai, Hao Wang, Penghui He, Chengjun Zhu, Qin Wang, Xuetuan Wei, Christopher T. Nomura, Shouwen Chen
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Microbial Cell Factories
Subjects:
Bacillus licheniformis
Signal peptide peptidase
Protein secretion
sppA
tepA
Online Access:http://link.springer.com/article/10.1186/s12934-017-0688-7

Internet

http://link.springer.com/article/10.1186/s12934-017-0688-7

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