Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens

Abstract Tibial dyschondroplasia (TD) is the most-prevalent leg disorder in fast-growing chickens; it is intractable and characterized by abnormal endochondral bone formation of proximal tibial growth-plates (TGPs). Previous studies have shown that bone is a highly vascularized tissue dependent on t...

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Bibliographic Details
Main Authors: Shu-cheng Huang, Li-hong Zhang, Jia-lu Zhang, Mujeeb Ur Rehman, Xiao-le Tong, Gang Qiu, Xiong Jiang, Mujahid Iqbal, Muhammad Shahzad, Yao-qin Shen, Jia-kui Li
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-22109-y