Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context
Theory predicts that pathogens will evolve towards intermediate virulence, yet the necessary trade-offs invoked by this theory have rarely been demonstrated empirically. Here, the authors show that dengue virus dynamics exhibit a trade-off between transmission and clearance rates.
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-04595-w |