Long-term effects of an acute and systemic administration of LPS on adult neurogenesis and spatial memory

Long-term effects of an acute and systemic administration of LPS on adult neurogenesis and spatial memory

The cognitive reserve is the capacity of the brain to maintain normal performance while exposed to insults or ageing. Increasing evidences point to a role for the interaction between inflammatory conditions and cognitive reserve status during Alzheimer's disease (AD) progression. The production...

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Bibliographic Details
Main Authors: Jorge eValero, Giorgia eMastrella, Ismael eNeiva, Silvia eSánchez, João O. Malva
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Neuroscience
Subjects:
Cognitive Reserve
Dentate Gyrus
Hippocampus
Inflammation
Microglia
3xTg-AD mouse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00083/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00083/full

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