Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.

Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.

Age-related macular degeneration (AMD) is a leading cause of legal blindness in the Western world. There are effective treatments for the vascular complications of neo-vascular AMD, but no effective therapies are available for the dry/atrophic form of the disease. A previously described transgenic C...

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Bibliographic Details
Main Authors: Ian Catchpole, Volker Germaschewski, Jaimie Hoh Kam, Peter Lundh von Leithner, Susannah Ford, Gerald Gough, Peter Adamson, Philip Overend, Jan Hilpert, Francisco J López, Yin Shan Eric Ng, Pete Coffey, Glen Jeffery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3682980?pdf=render

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http://europepmc.org/articles/PMC3682980?pdf=render

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