New insights of CYP1A in endogenous metabolism: a focus on single nucleotide polymorphisms and diseases
Cytochrome P450 1A (CYP1A), one of the major CYP subfamily in humans, not only metabolizes xenobiotics including clinical drugs and pollutants in the environment, but also mediates the biotransformation of important endogenous substances. In particular, some single nucleotide polymorphisms (SNPs) fo...
Main Authors: | Jian Lu, Xuyang Shang, Weiguo Zhong, Yuan Xu, Rong Shi, Xin Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
|
Series: | Acta Pharmaceutica Sinica B |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383519307701 |
Similar Items
-
Computational analysis of functional single nucleotide polymorphisms associated with the CYP11B2 gene.
by: Minyue Jia, et al.
Published: (2014-01-01) -
Allele frequencies of single nucleotide polymorphisms of clinically important drug-metabolizing enzymes CYP2C9, CYP2C19, and CYP3A4 in a Thai population
by: Rattanaporn Sukprasong, et al.
Published: (2021-06-01) -
Frequencies of CYP1A2 Single Nucleotide Polymorphism in Indonesian and Its Effect on Blood Pressure
by: Erizal Sugiono, et al.
Published: (2018-12-01) -
SINGLE NUCLEOTIDE POLYMORPHISMS (CYP11 ALPHA AND CYP17) AND SERUM SEX HORMONE BINDING GLOBULIN LEVELS IN NORMAL AND POLYCYSTIC OVARY SYNDROME
by: Nauman Aziz, et al.
Published: (2021-08-01) -
Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients
by: Li Jie-Hui, et al.
Published: (2012-09-01)