New insights of CYP1A in endogenous metabolism: a focus on single nucleotide polymorphisms and diseases

Cytochrome P450 1A (CYP1A), one of the major CYP subfamily in humans, not only metabolizes xenobiotics including clinical drugs and pollutants in the environment, but also mediates the biotransformation of important endogenous substances. In particular, some single nucleotide polymorphisms (SNPs) fo...

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Bibliographic Details
Main Authors: Jian Lu, Xuyang Shang, Weiguo Zhong, Yuan Xu, Rong Shi, Xin Wang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519307701