Human bone marrow mesenchymal stem cell-derived extracellular vesicles attenuate neuroinflammation evoked by focal brain injury in rats

Human bone marrow mesenchymal stem cell-derived extracellular vesicles attenuate neuroinflammation evoked by focal brain injury in rats

Abstract Background Ischemic stroke is the major cause of long-term severe disability and death in aged population. Cell death in the infarcted region of the brain induces immune reaction leading to further progression of tissue damage. Immunomodulatory function of mesenchymal stem cells (MSCs) has...

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Bibliographic Details
Main Authors: Sylwia Dabrowska, Anna Andrzejewska, Damian Strzemecki, Maurizio Muraca, Miroslaw Janowski, Barbara Lukomska
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Mesenchymal stem cells
Extracellular vesicles
Ischemic brain injury
Stroke
Intra-arterial transplantation
Immune response
Online Access:http://link.springer.com/article/10.1186/s12974-019-1602-5

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http://link.springer.com/article/10.1186/s12974-019-1602-5

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