Sphingolipids: Key Regulators of Apoptosis and Pivotal Players in Cancer Drug Resistance

Sphingolipids: Key Regulators of Apoptosis and Pivotal Players in Cancer Drug Resistance

Drug resistance elicited by cancer cells still constitutes a huge problem that frequently impairs the efficacy of both conventional and novel molecular therapies. Chemotherapy usually acts to induce apoptosis in cancer cells; therefore, the investigation of apoptosis control and of the mechanisms us...

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Bibliographic Details
Main Authors: Paola Giussani, Cristina Tringali, Laura Riboni, Paola Viani, Bruno Venerando
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:International Journal of Molecular Sciences
Subjects:
sphingolipids
ceramide
sphingosine-1P
gangliosides
globosides
sialidases
Online Access:http://www.mdpi.com/1422-0067/15/3/4356

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http://www.mdpi.com/1422-0067/15/3/4356

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