OX40 Regulates Both Innate and Adaptive Immunity and Promotes Nonalcoholic Steatohepatitis

OX40 Regulates Both Innate and Adaptive Immunity and Promotes Nonalcoholic Steatohepatitis

Summary: Both innate and adaptive immune cells are involved in the pathogenesis of nonalcoholic steatohepatitis (NASH), but the crosstalk between innate and adaptive immunity is largely unknown. Here we show that compared with WT mice, OX40−/− mice exhibit decreased liver fat accumulation, lobular i...

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Bibliographic Details
Main Authors: Guangyong Sun, Hua Jin, Chunpan Zhang, Hua Meng, Xinyan Zhao, Dan Wei, Xiaojuan Ou, Qianyi Wang, Shuxiang Li, Tianqi Wang, Xiaojing Sun, Wen Shi, Dan Tian, Kai Liu, Hufeng Xu, Yue Tian, Xinmin Li, Wei Guo, Jidong Jia, Zhongtao Zhang, Dong Zhang
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471831917X

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http://www.sciencedirect.com/science/article/pii/S221112471831917X

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