Activation of BK(Ca) channels in zoledronic acid-induced apoptosis of MDA-MB-231 breast cancer cells.

Activation of BK(Ca) channels in zoledronic acid-induced apoptosis of MDA-MB-231 breast cancer cells.

BACKGROUND: Zoledronic acid, one of the most potent nitrogen-containing biphosphonates, has been demonstrated to have direct anti-tumor and anti-metastatic properties in breast cancer in vitro and in vivo. In particular, tumor-cell apoptosis has been recognized to play an important role in the treat...

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Bibliographic Details
Main Authors: Yu-Guang Ma, Wen-Chao Liu, Shuo Dong, Cheng Du, Xiao-Jun Wang, Jin-Sheng Li, Xiao-Ping Xie, Li Wu, Da-Chang Ma, Zhi-Bin Yu, Man-Jiang Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3360057?pdf=render

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http://europepmc.org/articles/PMC3360057?pdf=render

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