Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.

Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.

All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Such knowledge would improve our ability to correctl...

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Bibliographic Details
Main Authors: Ashleigh E Schaffer, Brandon L Taylor, Jacqueline R Benthuysen, Jingxuan Liu, Fabrizio Thorel, Weiping Yuan, Yang Jiao, Klaus H Kaestner, Pedro L Herrera, Mark A Magnuson, Catherine Lee May, Maike Sander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3561089?pdf=render

Internet

http://europepmc.org/articles/PMC3561089?pdf=render

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