Allostatic breakdown of cascading homeostat systems: A computational approach

Homeostasis posits that physiological systems compensate setpoint deviations in an attempt to maintain a state of internal constancy. Allostasis, on the other hand, suggests that physiological regulation is more appropriately described by predictive modulatory actions that, by adjusting setpoints, a...

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Bibliographic Details
Main Authors: Alison Acevedo, Ioannis P. Androulakis
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017305303