Antigen-specific immunoglobulin variable region sequencing measures humoral immune response to vaccination in the equine neonate.

The value of prophylactic neonatal vaccination is challenged by the interference of passively transferred maternal antibodies and immune competence at birth. Taken our previous studies on equine B cell ontogeny, we hypothesized that the equine neonate generates a diverse immunoglobulin repertoire in...

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Bibliographic Details
Main Authors: Rebecca L Tallmadge, Steven C Miller, Stephen A Parry, Maria Julia B Felippe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5433778?pdf=render