Strategies to enhance oral delivery of amphotericin B: a comparison of uncoated and enteric-coated nanostructured lipid carriers

The oral delivery of amphotericin B (AmB) has remained a challenge due to its low solubility, permeability, and instability in gastric acidic pH. To solve these issues, herein, we reported a novel approach of using nanostructured lipid carriers (NLCs) and NLCs coating with Eudragit®L100-55 (Eu-NLCs)...

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Bibliographic Details
Main Authors: Pataranapa Nimtrakul, Pakawadee Sermsappasuk, Waree Tiyaboonchai
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2020.1785050