Chromosome Instability, Aging and Brain Diseases

Chromosome instability (CIN) has been repeatedly associated with aging and progeroid phenotypes. Moreover, brain-specific CIN seems to be an important element of pathogenic cascades leading to neurodegeneration in late adulthood. Alternatively, CIN and aneuploidy (chromosomal loss/gain) syndromes ex...

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Bibliographic Details
Main Authors: Ivan Y. Iourov, Yuri B. Yurov, Svetlana G. Vorsanova, Sergei I. Kutsev
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/5/1256