Determination of Mirabegron in rat plasma by UPLC–MS/MS after oral and intravenous administration
SUMMARY Mirabegron is a kind of β3 adrenergic receptor agonist which is an effective drug for the treatment of overactive bladder. In this research, a UPLC–MS/MS method is developed and validated for the study of mirabegron pharmacokinetic in rats. A protein precipitation method is applied for sampl...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Associação Médica Brasileira
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Series: | Revista da Associação Médica Brasileira |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302019000200141&lng=en&tlng=en |