Determination of Mirabegron in rat plasma by UPLC–MS/MS after oral and intravenous administration

SUMMARY Mirabegron is a kind of β3 adrenergic receptor agonist which is an effective drug for the treatment of overactive bladder. In this research, a UPLC–MS/MS method is developed and validated for the study of mirabegron pharmacokinetic in rats. A protein precipitation method is applied for sampl...

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Bibliographic Details
Main Authors: Lingdi Chen, Yu Zhang
Format: Article
Language:English
Published: Associação Médica Brasileira
Series:Revista da Associação Médica Brasileira
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302019000200141&lng=en&tlng=en