Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA

Gene, short hairpin RNA (shRNA) and small interfering RNA (siRNA) delivery can be particularly used for the treatment of diseases by the entry of genetic materials mammalian cells either to express new proteins or to suppress the expression of proteins, respectively. Polyamidoamine (PAMAM) Starburst...

Full description

Bibliographic Details
Main Authors: Hidetoshi Arima, Keiichi Motoyama, Taishi Higashi
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/4/1/130/