Inhaled colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria: A real-life experience in tertiary care hospitals in Saudi Arabia

Background: Nosocomial pneumonia (NP) due to multidrug-resistant (MDR) Gram-negative pathogens, has continued to rise over the last several decades. Parenteral administration of colistin results in poor alveolar penetration and subtherapeutic concentration; therefore, direct drug deposition at site...

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Bibliographic Details
Main Authors: Thamer A. Almangour, Basel Alenazi, Leen Ghonem, Abdullah A. Alhifany, Bassam A. Aldakheel, Alya Alruwaili
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420301493