UMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors.

UMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors.

Lentiviral vectors are widely used to investigate the biological properties of regulatory proteins and/or of leukaemia-associated oncogenes by stably enforcing their expression in hematopoietic stem and progenitor cells. In these studies it is critical to be able to monitor and/or sort the infected...

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Main Authors: Emanuela Chiarella, Giovanna Carrà, Stefania Scicchitano, Bruna Codispoti, Tiziana Mega, Michela Lupia, Daniela Pelaggi, Maria G Marafioti, Annamaria Aloisio, Marco Giordano, Giovanna Nappo, Cristina B Spoleti, Teresa Grillone, Emilia D Giovannone, Raffaella Spina, Francesca Bernaudo, Malcolm A S Moore, Heather M Bond, Maria Mesuraca, Giovanni Morrone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114795

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https://doi.org/10.1371/journal.pone.0114795

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