Host cell and expression engineering for development of an <it>E. coli </it>ketoreductase catalyst: Enhancement of formate dehydrogenase activity for regeneration of NADH

<p>Abstract</p> <p>Background</p> <p>Enzymatic NADH or NADPH-dependent reduction is a widely applied approach for the synthesis of optically active organic compounds. The overall biocatalytic conversion usually involves <it>in situ </it>regeneration of the e...

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Bibliographic Details
Main Authors: Mädje Katharina, Schmölzer Katharina, Nidetzky Bernd, Kratzer Regina
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/11/1/7