Breaking androgen receptor addiction of prostate cancer by targeting different functional domains in the treatment of advanced disease

In the last decade, treatment for castration-resistant prostate cancer has changed markedly, impacting symptom control and longevity for patients. However, a large proportion of cases progress despite androgen deprivation therapy and chemotherapy, while still being fit enough for several more lines...

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Bibliographic Details
Main Authors: Zoe R Maylin, Radu CB Nicolescu, Hardev Pandha, Mohammad Asim
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321001078