Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes

Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes

We investigated the genetic profiles of killer cell immunoglobulin-like receptors (KIRs) in Ebola virus–infected patients. We studied the relationship between KIR–human leukocyte antigen (HLA) combinations and the clinical outcomes of patients with Ebola virus disease (EVD). We genotyped KIRs and H...

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Bibliographic Details
Main Authors: Tony Wawina-Bokalanga, Bert Vanmechelen, Valentine Lhermitte, Joan Martí-Carreras, Valentijn Vergote, Fara Raymond Koundouno, Joseph Akoi-Boré, Ruth Thom, Tom Tipton, Kimberley Steeds, Kéita Balla Moussa, Ablam Amento, Lies Laenen, Sophie Duraffour, Martin Gabriel, Paula Ruibal, Yper Hall, Mandy Kader-Kondé, Stephan Günther, Guy Baele, Cesar Muñoz-Fontela, Johan Van Weyenbergh, Miles W. Carroll, Piet Maes
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2021-01-01
Series:Emerging Infectious Diseases
Subjects:
killer cell immunoglobulin-like receptor genes
killer cell immunoglobulin-like receptors
human leukocyte antigens class I
human leukocyte antigens
natural killer cells
Zaire ebolavirus
Online Access:https://wwwnc.cdc.gov/eid/article/27/1/20-2177_article

Internet

https://wwwnc.cdc.gov/eid/article/27/1/20-2177_article

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