Dynamics of immune parameters during the treatment of active tuberculosis showing negative interferon gamma response at the time of diagnosis

Dynamics of immune parameters during the treatment of active tuberculosis showing negative interferon gamma response at the time of diagnosis

Objectives: In the performance of interferon gamma release assays (IGRA) for the diagnosis of tuberculosis (TB) infection, false-negative results are a major obstacle. In active TB patients, treatment-dependent changes of the negative test results remain unknown. Methods: The treatment course of 19...

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Bibliographic Details
Main Authors: Ikumi Matsushita, Nguyen Thi Le Hang, Le Thi Hong, Do Bang Tam, Luu Thi Lien, Pham Huu Thuong, Vu Cao Cuong, Minako Hijikata, Nobuyuki Kobayashi, Shinsaku Sakurada, Kazue Higuchi, Nobuyuki Harada, Naoto Keicho
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:International Journal of Infectious Diseases
Subjects:
Interferon gamma release assay
False-negative result
Sensitivity
Interleukin 1 receptor antagonist
Interleukin 2
Interferon gamma-induced protein 10
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971215002313

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http://www.sciencedirect.com/science/article/pii/S1201971215002313

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