Optimization of amino acid replacement costs by mutational pressure in bacterial genomes
Abstract Mutations are considered a spontaneous and random process, which is important component of evolution because it generates genetic variation. On the other hand, mutations are deleterious leading to non-functional genes and energetically costly repairs. Therefore, one can expect that the muta...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-04-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-01130-7 |