Strategies for the Development of Conotoxins as New Therapeutic Leads

Peptide toxins typically bind to their target ion channels or receptors with high potency and selectivity, making them attractive leads for therapeutic development. In some cases the native peptide as it is found in the venom from which it originates can be used directly, but in many instances it is...

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Bibliographic Details
Main Authors: Jonathan B. Baell, Ryan M. Brady, Raymond S. Norton
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/7/2293