The Noradrenergic System of Aged GDNF Heterozygous Mice

Glial cell line-derived neurotrophic factor (GDNF) is a trophic factor for noradrenergic (NE) neurons of the pontine nucleus locus coeruleus (LC). Decreased function of the LC-NE neurons has been found during normal aging and in neurodegenerative disorders. We have previously shown that GDNF partici...

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Bibliographic Details
Main Authors: V. Zaman, Z. Li, L. Middaugh, S. Ramamoorthy, B. Rohrer, M. E. Nelson, A. C. Tomac, B. J. Hoffer, G. A. Gerhardt, A. Ch. Granholm DR.
Format: Article
Language:English
Published: SAGE Publishing 2003-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000003108746740