Aldosterone blockade in heart failure
Aldosterone plays a key role in the pathophysiology of heart failure. Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers may not suppress aldosterone production in the long term. This allows aldosterone to exert its effects on myocardial fibrosis and cardiac remodelling, e...
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| Format: | Article |
| Language: | English |
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Hindawi - SAGE Publishing
2004-03-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | http://jra.sagepub.com/content/5/1_suppl/S23.full.pdf |