Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease
<p>Abstract</p> <p>α-synuclein is a small soluble, cytosolic protein which associates with vesicular membranes. It is a component of intracellular Lewy bodies present in Parkinson's disease and a subset of Alzheimer's disease (AD). In addition, early studies identified a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-03-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/2/1/6 |