Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease

<p>Abstract</p> <p>α-synuclein is a small soluble, cytosolic protein which associates with vesicular membranes. It is a component of intracellular Lewy bodies present in Parkinson's disease and a subset of Alzheimer's disease (AD). In addition, early studies identified a...

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Bibliographic Details
Main Authors: Peethumnongsin Erica, Kallhoff Verena, Zheng Hui
Format: Article
Language:English
Published: BMC 2007-03-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/2/1/6