Thrombospondin-1 type 1 repeats in a model of inflammatory bowel disease: transcript profile and therapeutic effects.

Thrombospondin-1 (TSP-1) is a matricellular protein with regulatory functions in inflammation and cancer. The type 1 repeats (TSR) domains of TSP-1 have been shown to interact with a wide range of proteins that result in the anti-angiogenic and anti-tumor properties of TSP-1. To ascertain possible f...

Full description

Bibliographic Details
Main Authors: Zenaida P Lopez-Dee, Sridar V Chittur, Bhumi Patel, Rebecca Stanton, Michelle Wakeley, Brittany Lippert, Anastasya Menaker, Bethany Eiche, Robert Terry, Linda S Gutierrez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3318003?pdf=render