Germline Mutations and Polymorphisms in the Origins of Cancers in Women

Several female malignancies including breast, ovarian, and endometrial cancers can be characterized based on known somatic and germline mutations. Initiation and propagation of tumors reflect underlying genomic alterations such as mutations, polymorphisms, and copy number variations found in genes o...

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Bibliographic Details
Main Authors: Kim M. Hirshfield, Timothy R. Rebbeck, Arnold J. Levine
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2010/297671