Cytochrome P450 mRNA expressions along with in vitro differentiation of hepatocyte precursor cells from fetal, young and old rats.

Non-differentiated cells are attractive targets for cell therapy. During liver regeneration oval cells intensively proliferate and differentiate extending their metabolic activity. Hepatic cytochromes P450 (CYPs) can be linked either with metabolic activation of toxic compounds or drug metabolism. W...

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Bibliographic Details
Main Authors: Anna Wiaderkiewicz, Halina Koryciak-Komarska, Tomasz M Czekaj, Aleksandra Bryzek, Piotr Czekaj, Danuta Plewka, Aleksander L Sieroń
Format: Article
Language:English
Published: Via Medica 2010-06-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4243