Treatment of tumors with vitamin E suppresses myeloid derived suppressor cells and enhances CD8+ T cell-mediated antitumor effects.

Treatment of tumors with vitamin E suppresses myeloid derived suppressor cells and enhances CD8+ T cell-mediated antitumor effects.

Vitamin E has been shown to have strong anticarcinogenic properties, including antioxidant characteristics, making it an ideal candidate for use in combination with immunotherapies that modify the tumor microenvironment. The tumor microenvironment contains immunosuppressive components, which can be...

Full description

Bibliographic Details
Main Authors: Tae Heung Kang, Jayne Knoff, Wei-Hsi Yeh, Benjamin Yang, Chenguang Wang, Young Seob Kim, Tae Woo Kim, Tzyy-Choou Wu, Chien-Fu Hung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4114790?pdf=render

Internet

http://europepmc.org/articles/PMC4114790?pdf=render

Similar Items