Ve-ptp modulates vascular integrity by promoting adherens junction maturation.

BACKGROUND: Endothelial cell junctions control blood vessel permeability. Altered permeability can be associated with vascular fragility that leads to vessel weakness and haemorrhage formation. In vivo studies on the function of genes involved in the maintenance of vascular integrity are essential t...

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Bibliographic Details
Main Authors: Silvia Carra, Efrem Foglia, Solei Cermenati, Erica Bresciani, Costanza Giampietro, Carla Lora Lamia, Elisabetta Dejana, Monica Beltrame, Franco Cotelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3522677?pdf=render