Steroid-Functionalized Titanocenes: Docking Studies with Estrogen Receptor Alpha

Steroid-Functionalized Titanocenes: Docking Studies with Estrogen Receptor Alpha

Estrogen receptor alpha (ERα) is a transcription factor that is activated by hormones, with 17β-estradiol being its most active agonist endogenous ligand. ERα is also activated or inactivated by exogenous ligands. ER is overexpressed in hormone-dependent breast cancer, and one of the treatments for...

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Bibliographic Details
Main Authors: Li Ming Gao, Wilson Maldonado, Xiomara Narváez-Pita, José A. Carmona-Negrón, Jesus Olivero-Verbel, Enrique Meléndez
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Inorganics
Subjects:
steroid-functionalized titanocene
estrogen receptor
hormones
docking study
anticancer drug
Online Access:http://www.mdpi.com/2304-6740/4/4/38

Internet

http://www.mdpi.com/2304-6740/4/4/38

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