Mutations of mitochondrial genome in patients with carotid atherosclerosis

Mutations of mitochondrial genome in patients with carotid atherosclerosis

With aim of detection the spectrum of mitochondrial DNA mutations in patients with carotid atherosclerosis from Moscow Region, we used a Roche 454 high-throughput sequencing of the whole mitochondrial genome. We have found that the presence of a number of homoplasmic mitochondrial DNA mutations in g...

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Bibliographic Details
Main Authors: Margarita A Sazonova, Andrey V Zhelankin, Valeria A Barinova, Vasily V Sinyov, Zukhra B Khasanova, Yuri V Bobryshev, Anton Y Postnov, Igor A Sobenin, Alexander N Orekhov
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Genetics
Subjects:
Atherosclerosis
Mitochondria
Mutation
next generation sequencing
Mitochondrial Genome
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00111/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00111/full

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