Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells

Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells

Abstract Background Palmitic acid (PA) is a common saturated fatty acid that induces apoptosis in various types of cells, including testicular Leydig cells. There is evidence suggesting that PA is increased in patients with obesity and that PA-induced cell apoptosis may play an important role in obe...

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Bibliographic Details
Main Authors: Zhi Chen, Di Wen, Fen Wang, Chunbo Wang, Lei Yang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Leydig cell
Palmitic acid
Apoptosis
Curcumin
Endoplasmic reticulum stress
Online Access:http://link.springer.com/article/10.1186/s12958-019-0517-4

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http://link.springer.com/article/10.1186/s12958-019-0517-4

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