The dual role of HMGB1 in pancreatic cancer
Abstract. Pancreatic ductal adenocarcinoma (PDAC) is the most common type of exocrine pancreatic cancer with a 9% 5-year survival rate. High mobility group box 1 (HMGB1) is a nuclear protein that can act as a DNA chaperone in the sustainment of chromosome structure and function. When released into t...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health/LWW
2018-12-01
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Series: | Journal of Pancreatology |
Online Access: | http://journals.lww.com/10.1097/JP9.0000000000000002 |