The dual role of HMGB1 in pancreatic cancer

Abstract. Pancreatic ductal adenocarcinoma (PDAC) is the most common type of exocrine pancreatic cancer with a 9% 5-year survival rate. High mobility group box 1 (HMGB1) is a nuclear protein that can act as a DNA chaperone in the sustainment of chromosome structure and function. When released into t...

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Bibliographic Details
Main Authors: Rui Kang, MD, PhD, Daolin Tang, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2018-12-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000002