On the use of propensity scores in case of rare exposure

Abstract Background Observational post-marketing assessment studies often involve evaluating the effect of a rare treatment on a time-to-event outcome, through the estimation of a marginal hazard ratio. Propensity score (PS) methods are the most used methods to estimate marginal effect of an exposur...

Full description

Bibliographic Details
Main Authors: David Hajage, Florence Tubach, Philippe Gabriel Steg, Deepak L. Bhatt, Yann De Rycke
Format: Article
Language:English
Published: BMC 2016-03-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-016-0135-1