Sample size implications of mortality definitions in sepsis: a retrospective cohort study

Abstract Background Many randomized controlled trials (RCTs) employ mortality at a given time as a primary outcome. There are at least three common ways to measure 90-day mortality: first, all-location mortality, that is, all-cause mortality within 90 days of randomization at any location. Second, A...

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Bibliographic Details
Main Authors: Sushant Govindan, Hallie C. Prescott, Vineet Chopra, Theodore J. Iwashyna
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-018-2570-2